How to Get Off Methadone

It’s pretty common for people in opioid addiction treatment to stay on methadone for months, years, or even decades. Many want to be drug-free but do not know how to get off methadone. If you’re ready to move on, there’s a right way to do it. One that sets you up for long-term success. Our LGBTQ+ inpatient rehab gives members of the community an understanding space to fully reclaim their lives.

What Is Methadone?

Methadone is a synthetic opioid largely used to manage moderate to severe pain and to aid in opioid addiction treatment, particularly for heroin dependence. Like morphine and heroin, methadone interacts with opioid receptors in the brain. This drug helps to ease withdrawal symptoms and stabilize individuals undergoing addiction recovery.

Methadone has recognized medical uses but carries a high risk of dependence. Misusing methadone by taking it without a prescription or in excessive doses can lead to serious mental and physical health consequences. Other drugs in this category include morphine and hydrocodone.

Methadone Abuse

Although methadone is prescribed to reduce cravings and help manage opioid addiction, it is a tightly controlled substance. Those with a history of opioid addiction are at a higher risk of misusing methadone. Some individuals even develop a preference for methadone over their original drug of choice. Taking methadone without a prescription or exceeding the prescribed dose qualifies as abuse.

Unlike heroin or morphine, methadone is formulated to block the euphoric effects of opioids rather than enhance them. If someone in treatment attempts to use heroin while on methadone, the drug will suppress the high. However, methadone itself can produce mild euphoria, especially at high doses.

Common Side Effects of Methadone 

These range in severity depending on the dose taken and individual differences. Side effects include:

• Drowsiness
• Muscle weakness
• Dry mouth
• Sluggish reflexes
• Hypotension
• Lowered body temperature
• Reduced responsiveness to light
• Tolerance
• Dependence

Methadone Withdrawal Timeline

Days 1-2

Withdrawal symptoms usually appear after 30 hours following the last dose. However, onset can vary based on dosage and frequency of use. Symptoms during the first and second days often include chills, fever, muscle aches, rapid heartbeat, and general discomfort.

Days 3-8

By this time, cravings for methadone become more difficult to bear. Users may experience:

• Nausea
• Insomnia
• Irritability
• Anxiety
• Flu-like symptoms

Because methadone remains in the body for an extended period, withdrawal symptoms often peak between days 3 and 8. At this stage, additional effects such as vomiting, cramps, and deepening depression may emerge.

Days 9-15

After the peak phase, symptoms begin to subside but don’t disappear entirely. Lingering effects like diarrhea, irritability, and physical discomfort remain, while strong cravings persist. Depression may worsen, making it difficult for individuals to feel motivated or experience pleasure.

Days 15+

While many symptoms fade within 2-3 weeks, feelings of fatigue, anxiety, sleep disturbances, and cravings can linger. Even after the initial detox period of 3-6 weeks, some individuals experience post-acute withdrawal symptoms (PAWS), which may last for months or even up to two years. PAWS symptoms often include mood instability, depression, anxiety, trouble sleeping, and difficulty concentrating

What Does it Feel Like to Quit Methadone?

Once the body and brain get used to having methadone, quitting can trigger withdrawal symptoms. These symptoms occur because the system needs time to readjust to functioning without the drug. During this detox period, people experience many uncomfortable physical and psychological effects. The severity and duration of the withdrawal period vary based on factors such as how long the drug was used, at what dosage, and the individual's body chemistry.

Inpatient Methadone Rehab to Get off Methadone

Due to the difficulties of withdrawal, medical supervision is strongly recommended. Many inpatient treatment programs provide medically assisted detox to help ease symptoms and support a safer recovery process.

Inpatient rehab gives you a structured, immersive space to focus entirely on your recovery. Instead of juggling everyday life while trying to quit, you stay at a treatment center where you’re away from distractions—and from methadone itself.

Unlike outpatient programs, LGBT rehab offers a more in-depth approach, tackling both the physical and emotional sides of addiction. Plus, being surrounded by supportive staff and others on the same journey helps you build connections that can keep you motivated long after treatment ends.

Making the Most of Methadone Inpatient Rehab

If you're checking into a methadone rehab program, here are a few ways to get the best results:

• Be open with your counselors – Honesty helps them create a recovery plan that truly fits your needs.
• Stay engaged – Set goals, track your journey, and take part in activities that keep you committed to recovery.
• Focus on self-care – Recovery is not a one-day endeavor, it takes time. So, you should rest, recuperate, and pay attention to your mental well-being.
• Speak up when you need help – Don’t hesitate to reach out if you’re struggling.

Get Off Methadone With Q Space Detox

If methadone addiction is weighing you down, you’re not alone. Whether it started as pain management or a step toward quitting another drug, recovery is possible. If you or someone you care about is struggling with opioid addiction, reach out to a Q Space Detox Peer Support admissions advocate today via 305-745-7768 to discuss your rehab options and move toward healing.